Pathways associated with precocious puberty
Pathway |
Pathway ID |
Gene Symbol |
Entrez Gene ID |
Steroid hormone biosynthesis |
hsa00140 | CYP19A1, CYP21A2, HSD3B2
| 1588, 1589, 3284 |
Purine metabolism |
hsa00230 | PAPSS2
| 9060 |
Selenocompound metabolism |
hsa00450 | PAPSS2
| 9060 |
Sulfur metabolism |
hsa00920 | PAPSS2
| 9060 |
Metabolic pathways |
hsa01100 | CYP19A1, CYP21A2, HSD3B2, PAPSS2
| 1588, 1589, 3284, 9060 |
EGFR tyrosine kinase inhibitor resistance |
hsa01521 | IGF1, IGF1R
| 3479, 3480 |
Endocrine resistance |
hsa01522 | ESR1, GNAS, IGF1, IGF1R, NOTCH1
| 2099, 2778, 3479, 3480, 4851 |
RNA transport |
hsa03013 | FMR1
| 2332 |
PPAR signaling pathway |
hsa03320 | PPARG
| 5468 |
MAPK signaling pathway |
hsa04010 | IGF1, IGF1R, INS
| 3479, 3480, 3630 |
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